Use Caution/Monitor. iron sucrose decreases levels of demeclocycline by inhibition of GI absorption. FOR PATIENTS WEIGHING LESS THAN 50 kg: Administer Monoferric as 20 mg/kg actual body weight by intravenous infusion 20 minutes . Calculosaurus | Medical calculators for obstetrics and gynaecology Use the menu to browse through our clinical calculators. Use Caution/Monitor. Applies only to oral form of both agents. Copyright 2014 - 2023 The Calculator .CO |All Rights Reserved|Terms and Conditions of Use, Intravenous iron-dextran: therapeutic and experimental possibilities, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Treatment of iron deficiency anemia associated with gastrointestinal tract diseases, Diagnosis and management of iron deficiency anaemia: a clinical update. Use Caution/Monitor. Where: Medicine concentration Amount of active substance per a given volume of your drug. If we don't have the calculator you need we'll try to make it for you and add it to the website. Avoid or Use Alternate Drug. Applies only to oral form of both agents. Ensure the Intravenous Iron Checklist (see trust guideline) has been completed. Iron Deficiency In Pregnancy Calculator, Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator. Step 2: Calculation and administration of the maximum individual iron dose(s): . Serious - Use Alternative (1)iron sucrose decreases levels of tetracycline by inhibition of GI absorption. Contraindicated. Brand name: Venofer Drug class: Iron Preparations Chemical name: iron saccharate CAS number: 8047-67-4 Medically reviewed by Drugs.com on Oct 25, 2022. Here are the steps to follow for using this drug dosage calculator: First, enter the value of your Weight and choose the unit of measurement from the drop-down menu. trientine, iron sucrose. Aranesp (darbepoetin alfa) | Dosing Considerations After administration of iron dextran complex, evidence of a therapeutic response can be seen in a few days as an increase in the reticulocyte count. After total replacement dose completed, need for ongoing IV doses should be re-assessed monthly. Since this is less than the threshold of total dose of 20 mg/kg, the deficit can be eliminated with a single infusion. When administered via infusion, dilute up to 750 mg of iron in no more than 250 mL of sterile 0.9% sodium chloride injection, USP, such that the concentration of the infusion is not less than 2 mg of iron per mL and administer over at least 15 minutes. Use Caution/Monitor. Use Caution/Monitor. Diluted with 0.9% Sodium Chloride Injection at concentrations of 1 to 2 mg/mL, 2 doses of 300 mg/250 mL over 1.5 hrsplus1 dose of 400 mg/250 mL over 2.5 hrs. For iron maintenance treatment, administer Venofer, (2 years of age or older) with NDD-CKD or PDD-CKD who are on erythropoietin therapy for iron maintenance treatment. It varies from increases in dietary intake of iron (usually for prophylaxis purposes) to oral, intramuscular or intravenous therapy. Do not mix iron sucrose with other medications or TPN solution. Applies only to oral form of both agents. Sodium ferric gluconate complex injection [ Ferrlecit ] [package insert] - Elemental iron: 12.5 mg/mL (5 mL). VENOFER at IV doses up to 15 mg iron/kg/dose [about 10 times the maximum recommended human dose for a 70 kg person] given three times a week was found to have no effect on fertility . Use Caution/Monitor. Dosage Calculator This health tool computes the required parenteral iron replacement dose for the iron deficit extracted from the patient weight and hemoglobin level from complete blood count test. Divide the calculated dose by the patient's weight (IBW if BMI >30, or actual body weight (ABW) if BMI30) to ensure it does NOT exceed 20mg/kg. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time.Your dosage and length of treatment are based on your medical condition, age, and response to treatment. Parenteral iron dextran therapy. To provide clinicians with evidence-based guidance for iron therapy dosing in patients with iron deficiency anemia (IDA), we conducted a study examining the benefits of a higher cumulative dose of intravenous (IV) iron than what is typically administered. Contraindicated. Official Journal of the International Society of Nephrology. Results: Twelve children (6 females) aged 1.2-14 years (median age 8.9 years) received at least one dose of . Next Steps Evidence Creator Insights Dr. Andreas M. Ganzoni About the Creator Administer Venofer early during the dialysis session (generally within the first hour). Use Caution/Monitor. Applies only to oral form of both agents. Schweiz Med Wochenschr; 100(7):301-3. There is no resource limitation, as if the tool was hosted on your site, so all your users can make use of it 24/7; The necessary tool updates will take place in real time with no effort on your end; A single click install to embed it into your pages, whenever you need to use it. Baloxavir may bind to polyvalent cations resulting in decreased absorption. Use INFeD only in patients in whom clinical and laboratory investigations have established an iron deficient state not amenable to oral iron therapy. Alldredge BK, Corelli RL, Ernst ME, Guglielmo BJ, eds. with NDD-CKD or PDD-CKD who are on erythropoietin therapy for iron maintenance treatment, Hemodialysis-dependent chronic kidney disease (HDD-CKD)*, Non-dialysis-dependent chronic kidney disease (NDD-CKD), Peritoneal-dialysis-dependent chronic kidney disease (PDD-CKD), At a dose of 0.5 mg/kg, not to exceed 100 mg per dose, Given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at concentrations of 1 to 2 mg/mL and administered over 5 to 60 minutes, An increase in Hb concentration or a decrease in ESA dose is desired and. Maximum infusion rate: 100 mg / hour (Slow infusion rate of iron sucrose is recommended to minimize adverse reactions, especially hypotension) Frequency of infusion: Dose may be repeated up to 3 times weekly to provide total iron dose. iron sucrose decreases levels of levothyroxine by inhibition of GI absorption. The total amount of INFeD in mL required to treat the anemia and replenish iron stores may be approximated as follows: Adults and Children over 15 kg (33 lbs): See Dosage Table. Use Caution/Monitor. Iron Deficit - Multi-Calc - GlobalRPH - Medical Calculators, Clinicians Intravenous therapy is usually recommended in case of contraindications to oral iron, comorbidities that prevent absorption, chronic renal impairment or iron replacement needs to be rapid. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvdmVub2Zlci1pcm9uLXN1Y3Jvc2UtMzQyMTYy, View explanations for tiers and DICP. Applies only to oral form of both agents. Only administer Feraheme as an intravenous infusion over at least 15 minutes and only when personnel and therapies are immediately available for the treatment of anaphylaxis and other hypersensitivity reactions. UpToDate. Talk to your pharmacist for more details.During pregnancy, this medication should be used only when clearly needed. Serious - Use Alternative (1)iron sucrose decreases levels of fleroxacin by inhibition of GI absorption. Applies only to oral form of both agents. PDF Venofer - Food and Drug Administration Venofer Injection Dosage Guide - Drugs.com Compare formulary status to other drugs in the same class. Medicinal forms Minor/Significance Unknown. Coadministration of ciprofloxacin with multivalent cation-containing products may reduce the bioavailability of ciprofloxacin by 90%. Most Dosage Calculator - [100% Free] - Calculators.io The iron deficit calculator is useful as one of the determinations performed before iron replenishment therapy is initiated. *Administer early during the dialysis session. The dosage of Venofer is expressed in mg of elemental iron. Pain, swelling, or redness at the injection site may occur. iron sucrose decreases levels of tetracycline by inhibition of GI absorption. Applies only to oral form of both agents. Indications: Feraheme is indicated for the treatment of iron deficiency anemia (IDA) in adult patients: who have intolerance to oral iron or have had unsatisfactory response to oral iron or who have chronic kidney disease (CKD). J Med. Applies only to oral form of both agents. INFED- iron dextran injection [Package insert], Hemoglobin iron deficit (mg) = weight (kg) x (14 - Hgb) x (2.145) Note: Hbg (current hemoglobin level) units: (g/dL) Alternatively: Volume of product required (mL) = [weight (kg) x (14 - Hgb) x (2.145)] / C Where C= concentration of elemental iron (mg/ml) in the product being used: Iron dextran: 50 mg/mL. Iron Sucrose Monograph for Professionals - Drugs.com Patients with a history of drug allergy or multiple drug allergies may be at increased risk of anaphylactic-type reactions to INFeD. NOTES: Lab and/or medical tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be done while you are using this medication. Monitor Closely (1)iron sucrose decreases levels of levothyroxine by inhibition of GI absorption. 1. Fulminant symptoms may include general paleness, confusion or episodes of passing out. Applies only to oral form of both agents. Modify Therapy/Monitor Closely. May increase risk of hypotension. Applies only to oral form of both agents. The dose of Venofer must be individually calculated for each patient according to the total iron deficit calculated with the following Ganzoni formula, for example: Total iron deficit [mg] = BW [kg] x (target Hb - actual Hb) [g/dl] x 2.4* + storage iron [mg] Below 35 kg BW: 35 kg BW and above: Target Hb = 13 g/dl and storage iron = 15 mg/kg BW Applies only to oral form of both agents. Dosage: For patients weighing 50 kg (110 lb) or more: Give Injectafer in two doses separated by at least 7 days. Modify Therapy/Monitor Closely. Estimates the iron deficit in preparation for iron replacement based on patient weight and haemoglobin. Schweiz Med Wochenschr; 100(7):301-3. 1988 May;111(5):566-70. Applies only to oral form of both agents. Applies only to oral form of both agents. Most adults require a cumulative dose of elemental iron of at least 1 g. Iron replenishment is usually doneintravenously, via iron-dextran, iron sucrose or iron carboxymaltose. Copyright(c) 2023 First Databank, Inc. Creating an account is free and takes less than 1 minute. Serious - Use Alternative (1)iron sucrose decreases levels of levofloxacin by inhibition of GI absorption. Anemias. Iron stores are input as default 500 mg on the assumption that the patient weight is greater or equal to 35 kg (77 lbs). LBW = Lean body weight in kg. Applies only to oral form of both agents. Prescribing and dispensing information For iron sucrose A complex of ferric hydroxide with sucrose containing 2% (20 mg/mL) of iron. Use Caution/Monitor. Most reactions associated with intravenous iron preparations occur within 30 minutes of the completion of the infusion. Applies only to oral form of both agents. View the formulary and any restrictions for each plan. Calculation of Dosage of Nefrofer Total Iron Deficit (mg) Nefrofer (ml) = 20mg/ml Total Iron Deficit (mg) = Body weight (kg) x (Target Hb - Actual Hb) [g/l] x 0.24* + Depot Iron . If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. Minor (1)iron sucrose decreases levels of manganese by inhibition of GI absorption. Formula for calculating the required dose of iron sucrose A: Generally acceptable. Applies only to oral form of both agents. The Ganzoni equation is: Total iron deficit (mg) = Weight in kg x (Target Hb - Actual Hb in g/dL) x 2.4 + Iron stores In most cases, adult patients require a cumulative dose of elemental iron of at least 1 g. Most commonly, iron replenishment therapy is done intravenously: As total dose (iron-dextran or iron - carboxymaltose); Anemia of chronic disease (ACD), Calculation of the Total Iron Deficit equation appears in Cosmofer PI, Iron Dextran Dosing Calculator (iron deficit). For patients weighing less than 50 kg (110 lb): Give Injectafer in two doses separated by at least 7 days. Drug class: Iron products. Use Caution/Monitor. We have found the lower dose to be better tolerated in the second half of gestation. Drug: Comments: A: Acyclovir 1: Dose using a 40% adjusted body weight; Amikacin 2: Dose using a 40% adjusted body weight; Amphotericin B (liposomal) 3 Consider capping body weight to 100 kg; Atracurium 4: Dose using ideal body weight; The use of ideal body weight has been shown to be associated with a more predictable muscle strength recovery within 60 minutes and a lack of need for antagonism . Ferrlecit has been administered at sequential dialysis sessions by infusion or by slow intravenous injection during the dialysis session itself. Avoid or Use Alternate Drug. Included in the iron dextran package insert. Minor/Significance Unknown.iron sucrose increases levels of calcium acetate by enhancing GI absorption. Applies only to oral form of both agents. iron sucrose decreases levels of mycophenolate by inhibition of GI absorption. Intravenous Injection - PRIOR TO THE FIRST INTRAVENOUS INFeD THERAPEUTIC DOSE, ADMINISTER AN INTRAVENOUS TEST DOSE OF 0.5 ML. Maximum recommended single dose: 300 mg (See Prescriber's Orders). iron sucrose will decrease the level or effect of omadacycline by inhibition of GI absorption. Last updated on Jun 1, 2022. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Only administer Venofer when personnel and therapies are immediately available for the treatment of serious hypersensitivity reactions. The dosing for iron replacement treatment in pediatric patients with HDD-CKD has not been established. Iron Sucrose - Injection - Alberta Applies only to oral form of both agents. Applies only to oral form of both agents. To view formulary information first create a list of plans. We'll do this entirely for free, as long as the calculator has applications for women's health. Anemia of chronic disease (ACD), Calculation of the Total Iron Deficit equation appears in Cosmofer PI, Calculation of the Total Iron Deficit Alternative equation, Iron Dextran Dosing Calculator (iron deficit), HONcode standard for trust- worthy health, Pediatric Oncology: Diagnosis And Prognosis Communication, Pharmacosmos A/S, CosmoFer low molecular weight (Mw) iron dextran. FERAHEME met the predefined criteria for non-inferiority to Venofer . (3) Known hypersensitivity to Venofer. gymnema decreases levels of iron sucrose by inhibition of GI absorption. esomeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Use Caution/Monitor. Administer ciprofloxacin at least 2 hours before or 6 hours after using these products. Consult your doctor for more details.Remember that it is best to get your vitamins and minerals from food whenever possible. 2 DOSAGE & ADMINISTRATION Venofer must only be administered intravenously either by slow injection or by infusion. Use alternatives if available. The Ganzoni equation used by the iron deficiency calculator is the following: Total iron deficit (mg) = Weight in kg x (Target Hb - Actual Hb in g/dL) x 2.4 + Iron stores The recommendation is that most adults need a cumulative dose of elemental iron of at least 1 g. (2010) Diagnosis and management of iron deficiency anaemia: a clinical update. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. Applies only to oral form of both agents. 10th ed. 2. Applies only to oral form of both agents. Either increases effects of the other by pharmacodynamic synergism. For all products, slow initial infusion is prudent; the patient is observed closely for infusion reactions. Med J Aust. Hemoglobin iron deficit = 60 x (14 - 8) x (2.145) = 772 mg iron. Applies only to oral form of both agents. When iron sucrose was administered at deliberate overdoses to rabbit dams (up to 215 mg/kg/day) marked fetal/placental iron overload was noted. FERAHEME Dosing & Administration - Feraheme Excessive dosages of Venofer may lead to accumulation of iron in storage sites potentially leading to hemosiderosis. MISSED DOSE: It is important to get each dose of this medication as scheduled. These are real scientific discoveries about the nature of the human body, which can be invaluable to physicians taking care of patients. sodium sulfate/?magnesium sulfate/potassium chloride decreases levels of iron sucrose by inhibition of GI absorption. Individual plans may vary Controlled studies in pregnant women show no evidence of fetal risk. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. Copyright 2014 - 2023 The Calculator .CO |All Rights Reserved|Terms and Conditions of Use, Parenteral Iron Replacement For Iron Deficiency Anemia Calculator, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Clinical use of the total dose intravenous infusion of iron dextran, When is high-dose intravenous iron repletion needed? Venofer (Iron Sucrose Injection) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Prior to and at regular intervals during parenteral iron therapy, evaluate serum iron, hemoglobin, and hematocrit. Serious - Use Alternative (1)iron sucrose decreases levels of gemifloxacin by inhibition of GI absorption. 2012;2(4):288-335. Avoid or Use Alternate Drug. Use Caution/Monitor. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. Immune system disorders: Anaphylactic-type reactions, angioedema, Nervous system disorders: Convulsions, collapse, light-headedness, loss-of-consciousness, Respiratory, thoracic and mediastinal disorders: Bronchospasm, dyspnea, Musculoskeletal and connective tissue disorders: Back pain, swelling of the joints, General disorders and administration site conditions: Hyperhidrosis, Published studies on intravenous iron sucrose treatment after first trimester of pregnancy not shown adverse maternal or fetal outcomes; available reports of intravenous iron sucrose use in pregnant women during first trimester are insufficient to assess risk of major birth defects and miscarriage; iron deficiency anemia during pregnancy should be treated because there are risks to mother and fetus associated with untreated iron deficiency anemia (IDA) in pregnancy; risks to fetus associated with maternal severe hypersensitivity reactions, Severe adverse reactions including circulatory failure (severe hypotension, shock including in the context of anaphylactic reaction) may occur in pregnant women with parenteral iron products which may cause fetal bradycardia, especially during second and third trimester, Iron sucrose is present in human milk, and available published reports following exposure to 100-300 mg intravenous iron sucrose have not reported adverse reactions in breastfed infants; there are no data on effects on milk production, Developmental and health benefits of breastfeeding should be considered, along with mothers clinical need for treatment and any potential adverse effects on breastfed child from therapy or from underlying maternal condition.
Mount Timpanogos Deaths, Articles V
Mount Timpanogos Deaths, Articles V